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Dickens alludes to the recently enacted Anatomy Act when he has Oliver's mother's body disappear. Ruth Richardson, in her book , says "It is part of the subtext of the novel that the poor young woman who dies in its opening pages was being dissected while her son was being starved."

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One of the most dramatized of Dickens' works, Oliver Twist was appearing in 10 theaters in London before serialization of the novel was even completed. lists nearly 25 film versions, the first in 1906. Academy Award winning filmmaker Roman Polanski is the latest to bring the little orphan boy to the silver screen.

Dickens was severely criticized for introducing criminals and prostitutes in Oliver Twist, to which Dickens replied, in the preface to the Library Edition of Oliver Twist in 1858, "I saw no reason, when I wrote this book, why the very dregs of life, so long as their speech did not offend the ear, should not serve the purpose of a moral, at least as well as its froth and cream." The novel was well received but not with the adulation of Pickwick.

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Cruikshank had formerly provided illustrations for Dickens' but after Oliver Twist never illustrated another Dickens work. Author and artist remained friends through the 1840s until Cruikshank, formerly a heavy imbiber, became a zealous supporter of temperance. Dickens, in favor of moderation, took exception to Cruikshank's fanatical ravings on temperance and the friendship deteriorated.

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The illustrations for Oliver Twist by (1792-1878) are thought by many to be some of the finest for any Dickens novel. is a particularly effective illustration, conveying the feeling of isolation and anxiety of Fagin's last hours.

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Oliver Twist published in 3 volumes. Dickens revised the monthly parts for the publication which was the first published under Charles Dickens instead of Boz. Monthly serialization in Bentley's Miscellany continues.

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Dickens chose to publish Great Expectations in his weekly magazine rather than in the traditional monthly parts in order to revive slumping sales of the weekly. All the Year Round, which Dickens served as editor and publisher, featured general interest articles along with serialized novels by various authors. The novel serialized immediately preceding Great Expectations, A Long Day's Ride, by Charles Lever, was not popular with readers, producing the sales slump.

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Grieving for his beloved sister-in-law Dickens misses deadlines for the only time in his life. Monthly issues of and Oliver Twist are not published.

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Dickens modeled Miss Havisham's Satis House on . Charles II stayed at Restoration House on his return to England from Holland in 1660, restoring the English monarchy after the reign of Oliver Cromwell.