R is always different owing to the sum of man-made and ..



DIETARY cholesterol increases the plasma level of total and low-density lipoprotein (LDL) cholesterol and accelerates the development of atherosclerosis and its complications, but individual responses to a given change in the dietary cholesterol level vary widely. Such responses are reproducible to some extent, suggesting genetic as well as physiologic determinants. , Several genetic determinants have been identified in nonhuman primates. The homeostatic and regulatory mechanisms that maintain a relatively constant level of plasma cholesterol despite changes in dietary cholesterol intake include alterations in the efficiency of intestinal absorption and in the rates of cholesterol biosynthesis, LDL-receptor activity, secretion of cholesterol into bile, and hepatic conversion of cholesterol into bile acids, the chief metabolic product of cholesterol. , , ,

T1 - Reproducibility of cutaneous electrogastrography in the fasting state in man.

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According to Glenn Goldsmith, Denholm was a master of visual selection in a large field of open-pollinated blooms. Many of the flower breeding experts mentioned herein worked for Denholm at one time or another.

T1 - Reproducibility of heart rate changes following adenosine infusion in man

An 88-year-old man who lived in a retirement community complained only of loneliness since his wife's death. He was an articulate, well-educated elderly man, healthy except for an extremely poor memory without other specific neurologic deficits. He had been given a diagnosis of Alzheimer's disease and was intermittently depressed. His general health had been excellent, without notable symptoms. He had mild constipation. His weight had been constant at 82 to 86 kg (height, 1.87 m). He had no history (according to the patient and his personal physician of 15 years) of heart disease, stroke, or kidney disease except for an episode of mild chest pain three years earlier. The only objective change at that time was transient depression of the ST segments and T waves in the lateral leads on his electrocardiogram. The patient had been treated for angina and had had no recurrence. There was no history of gallstones or of symptoms of biliary tract disease, but no cholecystography or ultrasound examination had been done recently. His physician's records showed numerous serum cholesterol measurements that ranged from 3.88 to 5.18 mmol per liter (150 to 200 mg per deciliter).

The opportunities for both subtle and profound errorsin software and data management are boundless, yet they remain surprisingly underappreciated.

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24. Fogelman AM, Seager J, Hokom M, Edwards PA. . Separation of and cholesterol synthesis by human lymphocytes and monocytes . ; 20:–88.

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23. Cholesterol metabolism in the whole body. In: Myant NB. The biology of cholesterol and related steroids. London: William Heinemann Medical Books, 1981:466–80.

His language is vulgar and coarse;

28. Lin DS, Connor WE. . The long term effects of dietary cholesterol upon the plasma lipids, lipoproteins, cholesterol absorption, and the sterol balance in man: the demonstration of feedback inhibition of cholesterol biosynthesis and increased bile acid excretion . ; 21:–52.

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8. Katan MB, Beynen achéal, de Vries JHM, Nobels A. . Existence of consistent hypo- and hyperresponders to dietary cholesterol in man . ; 123:–34.

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7. McNamara DJ, Kolb R, Parker TS, et al. . Heterogeneity of cholesterol homeostasis in man: response to changes in dietary fat quality and cholesterol quantity . ; 79:–39.

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30. Kasäniemi YA, Ehnholm C, Miettinen TA. . Intestinal cholesterol absorption efficiency in man is related to apoprotein E phenotype . ; 80:–81.